CRD features
preserved or enhanced
new capabilities
beyond what CRD offers
clinical labs
already on the platform
countries served
across 4 continents
Seamlessly transition without data gaps. SNV, Indel, CNV, trio/family workflows, ACMG classification, HPO phenotyping, gene panels, and clinical reporting are fully preserved.
Accelerate discovery. DiagAI automatically extracts HPO terms from narratives. Driven by our UP² engine, the model captures 98% of causal variants within the top 10 candidates.
Access tools absent in legacy platforms. Protect data integrity with automated contamination checks, sample identity verification (ID-Check), and comprehensive WES coverage summaries.
Each step is carefully orchestrated by our dedicated team so you can transition with peace of mind.
Phase 1
Preparation
We audit your CRD setup and plan every detail of the migration.
Phase 2
Configuration
We set up GermVar to mirror and enhance your workflows.
Phase 3
Validation
We run your cases on both platforms and prove concordance.
Phase 4
Go-Live
You switch to production with dedicated support by your side.
What You Do
Share your current CRD configuration and workflows
Attend short training sessions (2-3 hours total)
Review the validation report we prepare
Give the green light to go live
What We Handle
Full audit of your CRD environment
Platform configuration and data migration
Gene panels, VKB, and filter profile setup
Run validation samples and produce concordance report
QC threshold configuration and testing
Deliver tailored training for your team
Post-go-live monitoring and dedicated support
All of your critical data, seamlessly transferred to the SeqOne Platform.
Want to see how GermVar maps to the CRD workflow?
Download our workflow mapping.
Gene Panels
Virtual panels -> In silico panels
Curated Variants
CVL -> Variant Knowledge Base
Filter Presets
Presets -> Filter Profiles
Users & Roles
Role mapping and permissions
The SeqOne Platform is more than a replacement for CRD.
It's a state-of-the-art, IVDR-certified platform built for the diagnostic workflows of today, and the growth opportunities of tomorrow.
A complete, IVDR-certified germline workflow covering everything CRD offered, and more. GermVar runs on the broader SeqOne Platform, so somatic and upcoming PGx workflows are ready when your lab needs them.
No surprise invoices. The SeqOne Platform offers transparent, predictable pricing so your lab always knows what to expect. Full cost visibility, no hidden fees.
All annotation databases are refreshed every quarter, so your team always works from the latest clinical evidence. No waiting for annual releases, no risk of outdated data.
GermVar Pipeline
One pipeline for Panels, WES & WGS. Multi-caller architecture with haplotype-based calling, CNV & SV detection, mitochondrial analysis, mosaic detection, and built-in STR expansion.
GenomeAlert Re-Analysis
Never miss a diagnosis. Automatically re-analyse unsolved cases against updated databases each month and alerts you when new evidence could change a patient's outcome.
ACMG Automation
Best-in-class ACMG criterion automation with ClinGen guidelines and gene-specific VCEP recommendations. Classifications follow the latest expert-curated rules out of the box.
Flexible Filtering
Comprehensive filter engine for SNV/Indels and CNV/SVs. Combine presets with Preset Combos, mark favorites, and share configurations across your entity or keep them private.
DiagAI Autofill
Generate clinical-scientist-level variant comments with a single click. Near report-ready narratives in seconds, drastically cutting manual writing time.
DiagAI Prioritization
Identify disease-causing variants with full transparency. UP² score breakdown via waterfall plots, phenotypic matching, and clear explanations of every ranking — so you understand every recommendation.
Your data stays yours—never shared, never sold. Our patented double-encryption system secures each patient file with a unique key for maximum data protection. You stay safe, compliant, and in control.
SeqOne Platform is a Class C, CE-IVDR certified in vitro diagnostic medical device, manufactured by SeqOne SAS (France). In the United Kingdom, SeqOne Platform is distributed under the Congenica brand by Congenica Ltd, a UK affiliate of SeqOne SAS. Congenica Ltd acts as the UK Responsible Person in accordance with UK MDR 2002.The company is certified under ISO 13485 for medical device manufacturer, and under ISO 27001 for information security and health data hosting.
Identify acquired mutations in cancers.
Pinpoint germline variants.
Detect microbial pathogens.
Validate Congenica with your own data, expert support, and zero commitment.
Pay-per-analysis with no hidden fees or volume constraints.
Access field specialists, multi-lingual assistance and hands-on guidance.
